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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
9.7
Human Site:
T232
Identified Species:
17.78
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
T232
A
R
P
E
V
K
W
T
H
E
Q
G
S
V
M
Chimpanzee
Pan troglodytes
XP_514624
382
43769
S23
D
D
S
P
R
T
P
S
N
T
P
S
T
E
A
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
T334
A
R
P
E
V
K
W
T
H
E
Q
G
S
V
M
Dog
Lupus familis
XP_542986
665
76981
T270
A
R
P
N
V
K
W
T
H
E
Q
G
S
V
M
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
K233
A
R
P
E
K
K
W
K
H
E
Q
G
S
I
E
Rat
Rattus norvegicus
XP_230789
677
77635
R288
A
R
P
D
I
K
W
R
H
E
Q
G
S
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
K223
A
R
Q
G
L
N
W
K
H
E
T
A
S
V
E
Frog
Xenopus laevis
Q6INN8
632
72730
K229
A
C
P
Q
K
K
F
K
H
E
S
A
S
V
A
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
K211
A
R
P
A
D
K
W
K
H
E
I
A
S
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
G204
L
I
T
E
L
I
S
G
K
P
F
D
F
Q
D
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
K210
I
R
P
D
F
K
H
K
H
E
H
L
S
V
L
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
A118
D
I
Q
T
V
K
L
A
G
L
L
H
D
V
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
L114
Y
D
L
Q
T
V
R
L
A
G
L
L
H
D
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
0
100
93.3
N.A.
73.3
73.3
N.A.
N.A.
46.6
46.6
60
N.A.
N.A.
N.A.
6.6
46.6
P-Site Similarity:
100
20
100
93.3
N.A.
80
86.6
N.A.
N.A.
53.3
60
60
N.A.
N.A.
N.A.
13.3
60
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
0
8
0
0
0
8
8
0
0
24
0
0
16
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
16
0
16
8
0
0
0
0
0
0
8
8
8
8
% D
% Glu:
0
0
0
31
0
0
0
0
0
70
0
0
0
8
24
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
8
8
0
39
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
70
0
8
8
8
0
0
% H
% Ile:
8
16
0
0
8
8
0
0
0
0
8
0
0
8
8
% I
% Lys:
0
0
0
0
16
70
0
39
8
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
16
0
8
8
0
8
16
16
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% M
% Asn:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
62
8
0
0
8
0
0
8
8
0
0
0
0
% P
% Gln:
0
0
16
16
0
0
0
0
0
0
39
0
0
8
8
% Q
% Arg:
0
62
0
0
8
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
8
0
0
8
8
70
0
0
% S
% Thr:
0
0
8
8
8
8
0
24
0
8
8
0
8
0
0
% T
% Val:
0
0
0
0
31
8
0
0
0
0
0
0
0
70
0
% V
% Trp:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _